Barbara Arbeithuber
Postdoctoral Scholar
Head of the Working Group, University Clinic of Gynaecology, Obstetrics and Gynaecological Endocrinology, Johannes Kepler University Linz, Austria
Interests
- Human molecular genetics
Education
-
Ph.D.,
Johannes Kepler University Linz, Austria
Biography
In Prof. Makova’s lab Barbara was interested in the accurate measurement of rare mutations. Her project was focused on the inheritance of mitochondrial DNA; particularly, analysis of de novo mutations in the germ line, as well as the inheritance of low-level variants.
Publications
B Arbeithuber, MA Cremona, J Hester, A Barrett, B Higgins, K Anthony, F Chiaromonte, FJ Diaz, KD Makova.
Advanced age increases frequencies of de novo mitochondrial mutations in macaque oocytes and somatic tissues.
P NATL ACAD SCI USA,
2022.
B Arbeithuber, J Hester, MA Cremona, N Stoler, A Zaidi, B Higgins, K Anthony, F Chiaromonte, FJ Diaz, KD Makova.
Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues.
PLOS BIOL,
2020.
N Stoler, B Arbeithuber, G Povysil, M Heinzl, R Salazar, KD Makova, I Tiemann-Boege, A Nekrutenko.
Family reunion via error correction: an efficient analysis of duplex sequencing data.
BMC BIOINFORMATICS,
2020.
A Barrett, B Arbeithuber, A Zaidi, P Wilton, IM Paul, R Nielsen, KD Makova.
Pronounced somatic bottleneck in mitochondrial DNA of human hair.
PHILOS T R SOC B,
2019.
A Zaidi, P Wilton, MS-W Su, IM Paul, B Arbeithuber, K Anthony, A Nekrutenko, R Nielsen, KD Makova.
Bottleneck and selection in the germline and maternal age influence transmission of mitochondrial DNA in human pedigrees.
P NATL ACAD SCI USA,
2019.
M Cechova, RS Harris, M Tomaszkiewicz, B Arbeithuber, F Chiaromonte, KD Makova.
High Satellite Repeat Turnover in Great Apes Studied with Short- and Long-read Technologies.
MOL BIOL EVOL,
2019.
B Arbeithuber, KD Makova, I Tiemann-Boege.
Artifactual mutations resulting from DNA lesions limit detection levels in ultrasensitive sequencing applications.
DNA RES,
2016.
N Stoler, B Arbeithuber, WM Guiblet, KD Makova, A Nekrutenko.
Streamlined analysis of duplex sequencing data with Du Novo.
GENOME BIOL,
2016.