Fig 1: Enrichment plot: E2F1_UP.V1_UP
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | de_results_collapsed |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | E2F1_UP.V1_UP |
| Enrichment Score (ES) | 0.22618644 |
| Normalized Enrichment Score (NES) | 1.2092825 |
| Nominal p-value | 0.22222222 |
| FDR q-value | 0.59772813 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ARHGAP8 | Rho GTPase activating protein 8 [Source:HGNC Symbol;Acc:HGNC:677] | 38 | 7.245 | 0.0412 | Yes |
| 2 | CASP7 | caspase 7 [Source:HGNC Symbol;Acc:HGNC:1508] | 100 | 6.016 | 0.0602 | Yes |
| 3 | LPIN2 | lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450] | 201 | 5.035 | 0.0510 | Yes |
| 4 | SLC7A1 | solute carrier family 7 member 1 [Source:HGNC Symbol;Acc:HGNC:11057] | 218 | 4.898 | 0.0838 | Yes |
| 5 | CRYZ | crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419] | 236 | 4.850 | 0.1157 | Yes |
| 6 | TINF2 | TERF1 interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGNC:11824] | 269 | 4.650 | 0.1382 | Yes |
| 7 | ADIPOR2 | adiponectin receptor 2 [Source:HGNC Symbol;Acc:HGNC:24041] | 284 | 4.597 | 0.1696 | Yes |
| 8 | SLC20A1 | solute carrier family 20 member 1 [Source:HGNC Symbol;Acc:HGNC:10946] | 293 | 4.572 | 0.2038 | Yes |
| 9 | NAB1 | NGFI-A binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7626] | 323 | 4.455 | 0.2262 | Yes |
| 10 | ZFPM1 | "zinc finger protein, FOG family member 1 [Source:HGNC Symbol;Acc:HGNC:19762]" | 428 | 4.056 | 0.2067 | No |
| 11 | EVL | Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234] | 524 | 3.812 | 0.1898 | No |
| 12 | BRCA2 | BRCA2 DNA repair associated [Source:HGNC Symbol;Acc:HGNC:1101] | 539 | 3.778 | 0.2143 | No |
| 13 | CHAF1B | chromatin assembly factor 1 subunit B [Source:HGNC Symbol;Acc:HGNC:1911] | 622 | 3.617 | 0.2024 | No |
| 14 | PLK4 | polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397] | 673 | 3.530 | 0.2063 | No |
| 15 | MCM4 | minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:HGNC:6947] | 740 | 3.419 | 0.2010 | No |
| 16 | SIRPA | signal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662] | 910 | -3.394 | 0.1426 | No |
| 17 | BCL2 | BCL2 apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:990] | 1123 | -3.723 | 0.0648 | No |
| 18 | TPD52 | tumor protein D52 [Source:HGNC Symbol;Acc:HGNC:12005] | 1655 | -5.044 | -0.1660 | No |
| 19 | KRT72 | keratin 72 [Source:HGNC Symbol;Acc:HGNC:28932] | 1727 | -5.336 | -0.1578 | No |
| 20 | NBL1 | "NBL1, DAN family BMP antagonist [Source:HGNC Symbol;Acc:HGNC:7650]" | 1782 | -5.656 | -0.1381 | No |
| 21 | NOCT | nocturnin [Source:HGNC Symbol;Acc:HGNC:14254] | 1831 | -6.018 | -0.1124 | No |
| 22 | TPM2 | tropomyosin 2 [Source:HGNC Symbol;Acc:HGNC:12011] | 1853 | -6.209 | -0.0712 | No |
| 23 | ITSN1 | intersectin 1 [Source:HGNC Symbol;Acc:HGNC:6183] | 1871 | -6.382 | -0.0264 | No |
| 24 | VEGFA | vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680] | 1959 | -9.042 | 0.0046 | No |
