Fig 1: Enrichment plot: RPS14_DN.V1_UP
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | de_results_collapsed |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | RPS14_DN.V1_UP |
| Enrichment Score (ES) | -0.302426 |
| Normalized Enrichment Score (NES) | -2.2170904 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.060940903 |
| FWER p-Value | 0.086 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | LINC00461 | long intergenic non-protein coding RNA 461 [Source:HGNC Symbol;Acc:HGNC:42810] | 22 | 7.979 | 0.0138 | No |
| 2 | GFI1 | growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237] | 54 | 6.952 | 0.0196 | No |
| 3 | NKG7 | natural killer cell granule protein 7 [Source:HGNC Symbol;Acc:HGNC:7830] | 67 | 6.677 | 0.0346 | No |
| 4 | TNFRSF9 | TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924] | 82 | 6.424 | 0.0476 | No |
| 5 | CCL2 | C-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10618] | 190 | 5.094 | 0.0076 | No |
| 6 | SH2D2A | SH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821] | 191 | 5.081 | 0.0238 | No |
| 7 | GPR137B | G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862] | 217 | 4.910 | 0.0263 | No |
| 8 | ARHGEF3 | Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683] | 240 | 4.829 | 0.0300 | No |
| 9 | PTPN22 | protein tyrosine phosphatase non-receptor type 22 [Source:HGNC Symbol;Acc:HGNC:9652] | 334 | 4.419 | -0.0047 | No |
| 10 | ARHGAP25 | Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951] | 482 | 3.920 | -0.0695 | No |
| 11 | CRTAM | cytotoxic and regulatory T cell molecule [Source:HGNC Symbol;Acc:HGNC:24313] | 495 | 3.897 | -0.0634 | No |
| 12 | IFI16 | interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395] | 643 | 3.580 | -0.1292 | No |
| 13 | BCL2A1 | BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991] | 829 | -3.282 | -0.2160 | No |
| 14 | SEPTIN10 | septin 10 [Source:HGNC Symbol;Acc:HGNC:14349] | 859 | -3.315 | -0.2207 | No |
| 15 | SIRPA | signal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662] | 910 | -3.394 | -0.2361 | No |
| 16 | KYNU | kynureninase [Source:HGNC Symbol;Acc:HGNC:6469] | 955 | -3.458 | -0.2482 | No |
| 17 | TNFAIP2 | TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895] | 1021 | -3.573 | -0.2710 | No |
| 18 | PILRA | paired immunoglobin like type 2 receptor alpha [Source:HGNC Symbol;Acc:HGNC:20396] | 1056 | -3.618 | -0.2774 | No |
| 19 | SESN1 | sestrin 1 [Source:HGNC Symbol;Acc:HGNC:21595] | 1095 | -3.685 | -0.2856 | No |
| 20 | PADI2 | peptidyl arginine deiminase 2 [Source:HGNC Symbol;Acc:HGNC:18341] | 1128 | -3.728 | -0.2906 | Yes |
| 21 | ITGAM | integrin subunit alpha M [Source:HGNC Symbol;Acc:HGNC:6149] | 1130 | -3.731 | -0.2792 | Yes |
| 22 | HLA-DMB | "major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935]" | 1134 | -3.740 | -0.2689 | Yes |
| 23 | KCTD12 | potassium channel tetramerization domain containing 12 [Source:HGNC Symbol;Acc:HGNC:14678] | 1139 | -3.751 | -0.2591 | Yes |
| 24 | SPINT1 | "serine peptidase inhibitor, Kunitz type 1 [Source:HGNC Symbol;Acc:HGNC:11246]" | 1146 | -3.763 | -0.2503 | Yes |
| 25 | CD9 | CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709] | 1148 | -3.766 | -0.2388 | Yes |
| 26 | SFXN3 | sideroflexin 3 [Source:HGNC Symbol;Acc:HGNC:16087] | 1149 | -3.768 | -0.2269 | Yes |
| 27 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2597] | 1186 | -3.830 | -0.2336 | Yes |
| 28 | CLEC5A | C-type lectin domain containing 5A [Source:HGNC Symbol;Acc:HGNC:2054] | 1233 | -3.932 | -0.2453 | Yes |
| 29 | CTSH | cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535] | 1253 | -3.981 | -0.2426 | Yes |
| 30 | PLK2 | polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699] | 1261 | -4.002 | -0.2335 | Yes |
| 31 | TFEC | transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754] | 1273 | -4.017 | -0.2265 | Yes |
| 32 | AIF1 | allograft inflammatory factor 1 [Source:HGNC Symbol;Acc:HGNC:352] | 1288 | -4.058 | -0.2210 | Yes |
| 33 | VNN1 | vanin 1 [Source:HGNC Symbol;Acc:HGNC:12705] | 1326 | -4.135 | -0.2273 | Yes |
| 34 | IGFBP7 | insulin like growth factor binding protein 7 [Source:HGNC Symbol;Acc:HGNC:5476] | 1329 | -4.139 | -0.2152 | Yes |
| 35 | CSTA | cystatin A [Source:HGNC Symbol;Acc:HGNC:2481] | 1341 | -4.166 | -0.2077 | Yes |
| 36 | ST3GAL6 | "ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080]" | 1345 | -4.180 | -0.1960 | Yes |
| 37 | COLEC12 | collectin subfamily member 12 [Source:HGNC Symbol;Acc:HGNC:16016] | 1378 | -4.266 | -0.1992 | Yes |
| 38 | CPM | carboxypeptidase M [Source:HGNC Symbol;Acc:HGNC:2311] | 1468 | -4.485 | -0.2317 | Yes |
| 39 | FBN2 | fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604] | 1492 | -4.531 | -0.2294 | Yes |
| 40 | ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif 6 [Source:HGNC Symbol;Acc:HGNC:222] | 1537 | -4.698 | -0.2376 | Yes |
| 41 | CDKN1A | cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784] | 1544 | -4.715 | -0.2257 | Yes |
| 42 | PLA2G7 | phospholipase A2 group VII [Source:HGNC Symbol;Acc:HGNC:9040] | 1554 | -4.742 | -0.2154 | Yes |
| 43 | JAG1 | jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188] | 1556 | -4.748 | -0.2008 | Yes |
| 44 | NCF2 | neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661] | 1562 | -4.758 | -0.1883 | Yes |
| 45 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1590 | -4.847 | -0.1871 | Yes |
| 46 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 1649 | -5.024 | -0.2016 | Yes |
| 47 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 1652 | -5.032 | -0.1866 | Yes |
| 48 | CAPG | "capping actin protein, gelsolin like [Source:HGNC Symbol;Acc:HGNC:1474]" | 1696 | -5.173 | -0.1928 | Yes |
| 49 | CTSS | cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545] | 1698 | -5.173 | -0.1768 | Yes |
| 50 | RAB31 | "RAB31, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9771]" | 1700 | -5.188 | -0.1609 | Yes |
| 51 | TM6SF1 | transmembrane 6 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11860] | 1724 | -5.316 | -0.1561 | Yes |
| 52 | CXCL8 | C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025] | 1740 | -5.411 | -0.1467 | Yes |
| 53 | ATP8B4 | ATPase phospholipid transporting 8B4 (putative) [Source:HGNC Symbol;Acc:HGNC:13536] | 1750 | -5.465 | -0.1341 | Yes |
| 54 | CLEC7A | C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558] | 1753 | -5.478 | -0.1177 | Yes |
| 55 | DMXL2 | Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938] | 1763 | -5.534 | -0.1049 | Yes |
| 56 | MS4A6A | membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375] | 1783 | -5.656 | -0.0969 | Yes |
| 57 | KBTBD11 | kelch repeat and BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:29104] | 1792 | -5.701 | -0.0829 | Yes |
| 58 | F5 | coagulation factor V [Source:HGNC Symbol;Acc:HGNC:3542] | 1814 | -5.922 | -0.0751 | Yes |
| 59 | LY86 | lymphocyte antigen 86 [Source:HGNC Symbol;Acc:HGNC:16837] | 1816 | -5.947 | -0.0568 | Yes |
| 60 | BST1 | bone marrow stromal cell antigen 1 [Source:HGNC Symbol;Acc:HGNC:1118] | 1842 | -6.111 | -0.0505 | Yes |
| 61 | PID1 | phosphotyrosine interaction domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26084] | 1865 | -6.321 | -0.0419 | Yes |
| 62 | ANPEP | "alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]" | 1887 | -6.541 | -0.0322 | Yes |
| 63 | TGFBI | transforming growth factor beta induced [Source:HGNC Symbol;Acc:HGNC:11771] | 1893 | -6.664 | -0.0136 | Yes |
| 64 | GPR183 | G protein-coupled receptor 183 [Source:HGNC Symbol;Acc:HGNC:3128] | 1929 | -7.298 | -0.0088 | Yes |
| 65 | CR1 | complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334] | 1958 | -9.041 | 0.0053 | Yes |
