Fig 1: Enrichment plot: STK33_NOMO_DN
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | de_results_collapsed |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | STK33_NOMO_DN |
| Enrichment Score (ES) | -0.2872507 |
| Normalized Enrichment Score (NES) | -1.8951541 |
| Nominal p-value | 0.014516129 |
| FDR q-value | 0.12089342 |
| FWER p-Value | 0.461 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | SATB2 | SATB homeobox 2 [Source:HGNC Symbol;Acc:HGNC:21637] | 3 | 9.805 | 0.0357 | No |
| 2 | RORB | RAR related orphan receptor B [Source:HGNC Symbol;Acc:HGNC:10259] | 11 | 8.965 | 0.0661 | No |
| 3 | PIK3R3 | phosphoinositide-3-kinase regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:8981] | 19 | 8.193 | 0.0936 | No |
| 4 | PTPRCAP | protein tyrosine phosphatase receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667] | 178 | 5.174 | 0.0309 | No |
| 5 | MFSD6 | major facilitator superfamily domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24711] | 232 | 4.852 | 0.0217 | No |
| 6 | SLC9B2 | solute carrier family 9 member B2 [Source:HGNC Symbol;Acc:HGNC:25143] | 256 | 4.738 | 0.0277 | No |
| 7 | SLAIN1 | SLAIN motif family member 1 [Source:HGNC Symbol;Acc:HGNC:26387] | 294 | 4.562 | 0.0257 | No |
| 8 | DGKZ | diacylglycerol kinase zeta [Source:HGNC Symbol;Acc:HGNC:2857] | 312 | 4.492 | 0.0339 | No |
| 9 | NHLRC2 | NHL repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:24731] | 357 | 4.326 | 0.0274 | No |
| 10 | TRIM58 | tripartite motif containing 58 [Source:HGNC Symbol;Acc:HGNC:24150] | 391 | 4.186 | 0.0261 | No |
| 11 | ITGB7 | integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162] | 527 | 3.808 | -0.0298 | No |
| 12 | SLC25A32 | solute carrier family 25 member 32 [Source:HGNC Symbol;Acc:HGNC:29683] | 654 | 3.554 | -0.0820 | No |
| 13 | MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6863] | 810 | 3.299 | -0.1504 | No |
| 14 | LRRK2 | leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618] | 866 | -3.326 | -0.1664 | No |
| 15 | ADGRA2 | adhesion G protein-coupled receptor A2 [Source:HGNC Symbol;Acc:HGNC:17849] | 875 | -3.337 | -0.1579 | No |
| 16 | PLXND1 | plexin D1 [Source:HGNC Symbol;Acc:HGNC:9107] | 898 | -3.374 | -0.1565 | No |
| 17 | PIP4P2 | "phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:25452]" | 924 | -3.414 | -0.1566 | No |
| 18 | FBLN7 | fibulin 7 [Source:HGNC Symbol;Acc:HGNC:26740] | 934 | -3.430 | -0.1483 | No |
| 19 | GPAT2 | "glycerol-3-phosphate acyltransferase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:27168]" | 1050 | -3.610 | -0.1945 | No |
| 20 | BCL2 | BCL2 apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:990] | 1123 | -3.723 | -0.2179 | No |
| 21 | PADI2 | peptidyl arginine deiminase 2 [Source:HGNC Symbol;Acc:HGNC:18341] | 1128 | -3.728 | -0.2059 | No |
| 22 | ACP3 | acid phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:125] | 1215 | -3.885 | -0.2359 | No |
| 23 | CLEC5A | C-type lectin domain containing 5A [Source:HGNC Symbol;Acc:HGNC:2054] | 1233 | -3.932 | -0.2299 | No |
| 24 | ST14 | ST14 transmembrane serine protease matriptase [Source:HGNC Symbol;Acc:HGNC:11344] | 1344 | -4.179 | -0.2714 | Yes |
| 25 | PRAM1 | PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091] | 1353 | -4.205 | -0.2596 | Yes |
| 26 | ALOX5 | arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435] | 1358 | -4.214 | -0.2456 | Yes |
| 27 | LINC00926 | long intergenic non-protein coding RNA 926 [Source:HGNC Symbol;Acc:HGNC:27514] | 1406 | -4.329 | -0.2537 | Yes |
| 28 | HK3 | hexokinase 3 [Source:HGNC Symbol;Acc:HGNC:4925] | 1418 | -4.360 | -0.2428 | Yes |
| 29 | CCR7 | C-C motif chemokine receptor 7 [Source:HGNC Symbol;Acc:HGNC:1608] | 1465 | -4.464 | -0.2499 | Yes |
| 30 | SIRPB2 | signal regulatory protein beta 2 [Source:HGNC Symbol;Acc:HGNC:16247] | 1475 | -4.498 | -0.2375 | Yes |
| 31 | FAM241A | family with sequence similarity 241 member A [Source:HGNC Symbol;Acc:HGNC:26813] | 1476 | -4.500 | -0.2204 | Yes |
| 32 | TMTC2 | transmembrane O-mannosyltransferase targeting cadherins 2 [Source:HGNC Symbol;Acc:HGNC:25440] | 1491 | -4.530 | -0.2104 | Yes |
| 33 | FBN2 | fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604] | 1492 | -4.531 | -0.1932 | Yes |
| 34 | FAM117B | family with sequence similarity 117 member B [Source:HGNC Symbol;Acc:HGNC:14440] | 1493 | -4.534 | -0.1760 | Yes |
| 35 | MTARC1 | mitochondrial amidoxime reducing component 1 [Source:HGNC Symbol;Acc:HGNC:26189] | 1508 | -4.592 | -0.1658 | Yes |
| 36 | SYDE2 | synapse defective Rho GTPase homolog 2 [Source:HGNC Symbol;Acc:HGNC:25841] | 1553 | -4.742 | -0.1708 | Yes |
| 37 | FLT3 | fms related receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765] | 1555 | -4.746 | -0.1533 | Yes |
| 38 | JDP2 | Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546] | 1611 | -4.927 | -0.1632 | Yes |
| 39 | CHML | CHM like Rab escort protein [Source:HGNC Symbol;Acc:HGNC:1941] | 1636 | -4.982 | -0.1568 | Yes |
| 40 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 1640 | -4.995 | -0.1394 | Yes |
| 41 | F13A1 | coagulation factor XIII A chain [Source:HGNC Symbol;Acc:HGNC:3531] | 1649 | -5.024 | -0.1245 | Yes |
| 42 | ALCAM | activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400] | 1652 | -5.032 | -0.1064 | Yes |
| 43 | SDK2 | sidekick cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:19308] | 1734 | -5.373 | -0.1282 | Yes |
| 44 | RETREG1 | reticulophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:25964] | 1749 | -5.461 | -0.1147 | Yes |
| 45 | OSBPL1A | oxysterol binding protein like 1A [Source:HGNC Symbol;Acc:HGNC:16398] | 1863 | -6.309 | -0.1497 | Yes |
| 46 | ANPEP | "alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]" | 1887 | -6.541 | -0.1368 | Yes |
| 47 | BTBD11 | BTB domain containing 11 [Source:HGNC Symbol;Acc:HGNC:23844] | 1915 | -7.026 | -0.1242 | Yes |
| 48 | NEO1 | neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754] | 1920 | -7.138 | -0.0992 | Yes |
| 49 | AFF3 | AF4/FMR2 family member 3 [Source:HGNC Symbol;Acc:HGNC:6473] | 1922 | -7.150 | -0.0725 | Yes |
| 50 | SETD7 | "SET domain containing 7, histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:30412]" | 1924 | -7.186 | -0.0457 | Yes |
| 51 | BEX2 | brain expressed X-linked 2 [Source:HGNC Symbol;Acc:HGNC:30933] | 1955 | -8.750 | -0.0281 | Yes |
| 52 | CR1 | complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334] | 1958 | -9.041 | 0.0052 | Yes |
