Fig 1: Enrichment plot: TBK1.DF_DN
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | de_results_collapsed |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | TBK1.DF_DN |
| Enrichment Score (ES) | 0.28153694 |
| Normalized Enrichment Score (NES) | 1.6255696 |
| Nominal p-value | 0.026699029 |
| FDR q-value | 0.6137163 |
| FWER p-Value | 0.909 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | STOM | stomatin [Source:HGNC Symbol;Acc:HGNC:3383] | 29 | 7.574 | 0.0407 | Yes |
| 2 | MYO6 | myosin VI [Source:HGNC Symbol;Acc:HGNC:7605] | 46 | 7.081 | 0.0845 | Yes |
| 3 | CCNE2 | cyclin E2 [Source:HGNC Symbol;Acc:HGNC:1590] | 115 | 5.846 | 0.0924 | Yes |
| 4 | MBP | myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925] | 194 | 5.062 | 0.0893 | Yes |
| 5 | MFSD6 | major facilitator superfamily domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24711] | 232 | 4.852 | 0.1059 | Yes |
| 6 | SPRY2 | sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270] | 265 | 4.684 | 0.1238 | Yes |
| 7 | ZNF654 | zinc finger protein 654 [Source:HGNC Symbol;Acc:HGNC:25612] | 266 | 4.670 | 0.1581 | Yes |
| 8 | NF1 | neurofibromin 1 [Source:HGNC Symbol;Acc:HGNC:7765] | 381 | 4.223 | 0.1303 | Yes |
| 9 | GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:4125] | 406 | 4.134 | 0.1483 | Yes |
| 10 | BCL2L1 | BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992] | 425 | 4.064 | 0.1689 | Yes |
| 11 | C5orf22 | chromosome 5 open reading frame 22 [Source:HGNC Symbol;Acc:HGNC:25639] | 441 | 4.015 | 0.1907 | Yes |
| 12 | DENND1B | DENN domain containing 1B [Source:HGNC Symbol;Acc:HGNC:28404] | 514 | 3.838 | 0.1818 | Yes |
| 13 | ARMC1 | armadillo repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:17684] | 536 | 3.788 | 0.1988 | Yes |
| 14 | AMMECR1 | AMMECR nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:467] | 567 | 3.718 | 0.2106 | Yes |
| 15 | RFWD3 | ring finger and WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:25539] | 615 | 3.627 | 0.2130 | Yes |
| 16 | NFYB | nuclear transcription factor Y subunit beta [Source:HGNC Symbol;Acc:HGNC:7805] | 648 | 3.564 | 0.2227 | Yes |
| 17 | H1-4 | "H1.4 linker histone, cluster member [Source:HGNC Symbol;Acc:HGNC:4718]" | 682 | 3.514 | 0.2315 | Yes |
| 18 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 701 | 3.484 | 0.2478 | Yes |
| 19 | DNAJB14 | DnaJ heat shock protein family (Hsp40) member B14 [Source:HGNC Symbol;Acc:HGNC:25881] | 734 | 3.430 | 0.2565 | Yes |
| 20 | GTF2A1 | general transcription factor IIA subunit 1 [Source:HGNC Symbol;Acc:HGNC:4646] | 768 | 3.367 | 0.2642 | Yes |
| 21 | SEPHS2 | selenophosphate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:19686] | 783 | 3.339 | 0.2815 | Yes |
| 22 | FNBP1L | formin binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:20851] | 1072 | -3.642 | 0.1598 | No |
| 23 | KCTD3 | potassium channel tetramerization domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21305] | 1278 | -4.027 | 0.0836 | No |
| 24 | SCARB1 | scavenger receptor class B member 1 [Source:HGNC Symbol;Acc:HGNC:1664] | 1338 | -4.163 | 0.0838 | No |
| 25 | SLC39A8 | solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862] | 1357 | -4.214 | 0.1055 | No |
| 26 | SEMA3C | semaphorin 3C [Source:HGNC Symbol;Acc:HGNC:10725] | 1640 | -4.995 | -0.0033 | No |
| 27 | IL1RL1 | interleukin 1 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:5998] | 1660 | -5.050 | 0.0240 | No |
| 28 | HOOK1 | hook microtubule tethering protein 1 [Source:HGNC Symbol;Acc:HGNC:19884] | 1797 | -5.735 | -0.0040 | No |
| 29 | FOS | "Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796]" | 1840 | -6.093 | 0.0191 | No |
| 30 | OSBPL1A | oxysterol binding protein like 1A [Source:HGNC Symbol;Acc:HGNC:16398] | 1863 | -6.309 | 0.0542 | No |
