Fig 1: Enrichment plot: TGFB_UP.V1_DN
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | de_results_collapsed |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | TGFB_UP.V1_DN |
| Enrichment Score (ES) | 0.2863578 |
| Normalized Enrichment Score (NES) | 1.5893886 |
| Nominal p-value | 0.04845815 |
| FDR q-value | 0.4871626 |
| FWER p-Value | 0.948 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PIK3R3 | phosphoinositide-3-kinase regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:8981] | 19 | 8.193 | 0.0536 | Yes |
| 2 | ADRB2 | adrenoceptor beta 2 [Source:HGNC Symbol;Acc:HGNC:286] | 53 | 6.961 | 0.0905 | Yes |
| 3 | ARID5B | AT-rich interaction domain 5B [Source:HGNC Symbol;Acc:HGNC:17362] | 86 | 6.383 | 0.1235 | Yes |
| 4 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:HGNC:5411] | 188 | 5.103 | 0.1110 | Yes |
| 5 | JADE2 | jade family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:22984] | 263 | 4.694 | 0.1092 | Yes |
| 6 | SPRY2 | sprouty RTK signaling antagonist 2 [Source:HGNC Symbol;Acc:HGNC:11270] | 265 | 4.684 | 0.1449 | Yes |
| 7 | H2AC17 | H2A clustered histone 17 [Source:HGNC Symbol;Acc:HGNC:4735] | 288 | 4.594 | 0.1692 | Yes |
| 8 | SAP30 | Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532] | 296 | 4.557 | 0.2008 | Yes |
| 9 | PTCH1 | patched 1 [Source:HGNC Symbol;Acc:HGNC:9585] | 327 | 4.439 | 0.2197 | Yes |
| 10 | ANKMY2 | ankyrin repeat and MYND domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25370] | 330 | 4.432 | 0.2530 | Yes |
| 11 | IFIT2 | interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409] | 392 | 4.186 | 0.2540 | Yes |
| 12 | MLYCD | malonyl-CoA decarboxylase [Source:HGNC Symbol;Acc:HGNC:7150] | 393 | 4.179 | 0.2864 | Yes |
| 13 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:5407] | 701 | 3.484 | 0.1552 | No |
| 14 | PLEKHF1 | pleckstrin homology and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20764] | 776 | 3.345 | 0.1430 | No |
| 15 | ID1 | "inhibitor of DNA binding 1, HLH protein [Source:HGNC Symbol;Acc:HGNC:5360]" | 840 | -3.296 | 0.1361 | No |
| 16 | THBD | thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784] | 900 | -3.381 | 0.1319 | No |
| 17 | RGS2 | regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998] | 942 | -3.447 | 0.1375 | No |
| 18 | ATRNL1 | attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063] | 952 | -3.454 | 0.1596 | No |
| 19 | MITF | melanocyte inducing transcription factor [Source:HGNC Symbol;Acc:HGNC:7105] | 1267 | -4.011 | 0.0289 | No |
| 20 | FRMD4B | FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886] | 1445 | -4.423 | -0.0280 | No |
| 21 | MN1 | "MN1 proto-oncogene, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:7180]" | 1451 | -4.432 | 0.0037 | No |
| 22 | EVI2A | ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499] | 1590 | -4.847 | -0.0298 | No |
| 23 | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1 [Source:HGNC Symbol;Acc:HGNC:217] | 1597 | -4.878 | 0.0049 | No |
| 24 | FHL3 | four and a half LIM domains 3 [Source:HGNC Symbol;Acc:HGNC:3704] | 1644 | -5.004 | 0.0199 | No |
| 25 | ACKR3 | atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692] | 1764 | -5.541 | 0.0015 | No |
| 26 | ZNF512B | zinc finger protein 512B [Source:HGNC Symbol;Acc:HGNC:29212] | 1872 | -6.384 | -0.0041 | No |
| 27 | SPRY1 | sprouty RTK signaling antagonist 1 [Source:HGNC Symbol;Acc:HGNC:11269] | 1904 | -6.854 | 0.0330 | No |
